Rachel Gurrell Selected Research

PF-06372865

8/2019	Analgesic potential of PF-06372865, an α2/α3/α5 subtype-selective GABAA partial agonist, in humans.
1/2019	Photosensitive epilepsy: Robust clinical efficacy of a selective GABA potentiator.
1/2019	Pronounced antiepileptic activity of the subtype-selective GABAA -positive allosteric modulator PF-06372865 in the GAERS absence epilepsy model.
9/2018	A randomised, placebo-controlled clinical trial with the α2/3/5 subunit selective GABAA positive allosteric modulator PF-06372865 in patients with chronic low back pain.

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Rachel Gurrell Research Topics

Disease

3	Pain (Aches) 08/2019 - 01/2011
2	Seizures (Absence Seizure) 10/2022 - 01/2019
2	Epilepsy (Aura) 10/2022 - 01/2019
2	Neuralgia (Stump Neuralgia) 08/2019 - 01/2011
2	Gout 01/2018 - 08/2016
1	Partial Epilepsies (Epilepsy, Partial) 10/2022
1	Reflex Epilepsy (Photosensitive Epilepsy) 01/2019
1	Absence Epilepsy (Childhood Absence Epilepsy) 01/2019
1	Sleepiness 09/2018
1	Dizziness (Lightheadedness) 09/2018
1	Nausea 09/2018
1	Low Back Pain (Lumbago) 09/2018
1	Parkinson Disease (Parkinson's Disease) 06/2018
1	Arthritis (Polyarthritis) 01/2018
1	Hyperuricemia 01/2018
1	Acute Kidney Injury (Acute Renal Failure) 08/2016
1	Vascular System Injuries 01/2014
1	Cognitive Dysfunction 01/2011

Drug/Important Bio-Agent (IBA)

4	PF-06372865IBA 08/2019 - 09/2018
3	gamma-Aminobutyric Acid (GABA)IBA 01/2019 - 01/2011
2	Pregabalin (Lyrica)FDA Link 08/2019 - 01/2017
2	Analgesics (Analgesic Drugs)IBA 08/2019 - 01/2017
2	Uric Acid (Urate)IBA 01/2018 - 08/2016
1	brivaracetamIBA 10/2022
1	Lacosamide FDA Link 10/2022
1	Pharmaceutical PreparationsIBA 10/2022
1	BenzodiazepinesIBA 01/2019
1	Diazepam (Valium)FDA LinkGeneric 01/2019
1	Valproic Acid (Depakote)FDA LinkGeneric 01/2019
1	Anticonvulsants (Antiepileptic Drugs)IBA 01/2019
1	Aminobutyrates (Aminobutyric Acid)IBA 09/2018
1	Dopamine D1 Receptors (Dopamine D1 Receptor)IBA 06/2018
1	PF-06669571IBA 06/2018
1	Levodopa (L Dopa)FDA LinkGeneric 06/2018
1	Ibuprofen (Motrin)FDA LinkGeneric 01/2017
1	Phenytoin (Dilantin)FDA LinkGeneric 01/2017
1	EsketamineIBA 01/2017
1	Fentanyl (Sublimaze)FDA LinkGeneric 01/2017
1	urate transporterIBA 08/2016
1	Xanthine OxidaseIBA 08/2016
1	Fluorescein (Funduscein)FDA LinkGeneric 01/2014
1	GABA-A Receptors (GABA(A) Receptor)IBA 01/2011
1	7- (1,1- dimethylethyl)- 6- (2- ethyl- 2H- 1,2,4- triazol- 3- ylmethoxy)- 3- (2- fluorophenyl)- 1,2,4- triazolo(4,3- b)pyridazineIBA 01/2011
1	L 838,417IBA 01/2011

Therapy/Procedure

1	Therapeutics 10/2022
1	Electrodes (Electrode) 01/2019
1	Analgesia 01/2011